Research
“Our lab focus is on how vascular inflammation contributes to lung and lymphatic disease and to develop targeted therapeutics that can safely treat these conditions.” - Mark Nicolls
Research Areas
Lymphedema
Our group investigates the so-called 'third circulation', the lymphatics.
Emphysema/COPD
Our group recently found that loss of endothelial cell (EC) hypoxia inducible factor-2α (HIF-2α), induced by cigarette smoke, plays a key role in the development of emphysema.
Learn More About Emphysema/COPD >>
Lung Transplantation
Loss of the functional airway microvasculature predisposes lung transplants to chronic rejection.
Pulmonary Hypertension
Pulmonary Hypertension is a deadly disease, currently without a cure.